Lee Soo-jung, abandoned by her spouse, adopts Rena Jung and moves to the US, becoming a celebrity chef and manipulating others, hoping to marry Park Min-joon's adopted daughter Kang Yi-sol.
Yoo Jung and Hong Seol, struggling with a difficult relationship, are adopted into Jung's family, with talented musician Baek In-ho and materialistic older sister Baek In-ha also playing roles.
Kim Bok-joo and her competitive swimmer friend, Jung Joon-hyung, pursue their weightlifting dreams while balancing their college education and falling in love.
Three years after season one, Kim Sa-bu, a triple-board certified surgeon, chooses Woo Jin and Eun Jae over two other candidates, dealing with career hardships, personal issues, and falling in love.
Sim Woo-Joo's life is tumultuous after her father's mistress dies, and she plots revenge against her, while struggling with her emotions and falling in love with the mistress's son.
Michaela, a girl with a life-predicting ability, struggles to determine her remaining time until she meets Lee Do Ha, a chaebol obsessed with his life and money. Their bond highlights the importance of making every moment count.
Yoo Hye-jung rebels against unfavorable circumstances and pursues a doctor's career, with Hong Ji-hong as her mentor. Jin Seon-woo, a neurosurgeon, becomes enraged by Hye-jung's growing intimacy.