New technique can trace hazardous chemicals spread through fast-food wrappers in body

Washington DC: Researchers have come up with a new technique through which hazardous chemicals from fast-food wrappers in the body can be traced.

A team of scientists from University of Alabama and the University of Notre Dame have developed a new method that enables the researchers to radiolabel three forms of perfluorinated and polyfluorinated alkyl substances (PFAS) and track the fate of these chemicals when they enter the body.

This new method is a significant and timely advancement in identifying and tracking the PFASs, which are known to be harmful to the human body.

In February this year, these PFASs were found to be used extensively in fast-food wrapping paper at many popular chain restaurants.

Key points to know about this discovery, recent findings:

• In a study released in February showed that, of the more than 400 samples of packaging materials tested from many popular fast-food restaurants, PFASs were found in 56% of dessert and bread wrappers, 38% of sandwich and burger wrappers, and 20% of paperboard.
• Exposure to PFASs is linked to kidney and testicular cancer, elevated cholesterol, decreased fertility, and thyroid problems in adults.
• Exposure to PFASs is linked to adverse effects on growth, learning and behaviour and decreased immune response to vaccines in children.
• A new radio tracing method developed by UAB Radiology enabled researchers to discover that highly fluorinated, potentially toxic chemicals known as perfluorinated alkyl substances, or PFASs, were found in all body organs tested, including liver, stomach, leg bone, lungs, kidney, heart, skin, muscle, brain and other organs.
• Because tracing PFAS compounds conventionally is difficult, UAB Radiology developed a method to tag the intact PFAS compounds with a fluorine-18 radio tracer so researchers could see where the compound was going in the body and make sensitive measurements for the first time.

PFASs are often used in stain-resistant products, firefighting materials and nonstick cookware and not meant for ingestion. Previous studies have shown PFASs can migrate, contaminating the food and, when consumed, accumulating in the body.

“We are very excited about this technique, which borrows from our current work developing nuclear medicine imaging agents,” said first author Jennifer Burkemper. “This work can enable rapid screening of PFAS compounds to gain key insights into their biological fate.”

The study is published in the Journal of Environment Science and Technology.

(With ANI inputs)